Pathway Listing for Vibrio cholerae O1 biovar El Tor str. N16961 Sorted by Pathway Score

Overview

This page presents some of the evidence used to determine which pathways are present in Vibrio cholerae O1 biovar El Tor str. N16961. For each pathway, we show

• A diagram (the pathway evidence glyph) summarizing the presence of enzymes for each reaction in the pathway
• The normalized pathway score computed for the pathway
• The total number of reactions in the pathway
• The number of pathway reactions which an enzyme is present in Vibrio cholerae O1 biovar El Tor str. N16961
• The number of those reactions that appear in other pathways in Vibrio cholerae O1 biovar El Tor str. N16961 (and hence are not unique to the particular pathway)
• The number of reactions designated in MetaCyc as key indicators for the presence of this pathway, for which enzymes are present in Vibrio cholerae O1 biovar El Tor str. N16961
• Whether this organism is within the taxonomic groups (if any) designated in MetaCyc as the taxonomic range of this pathway

Key to Pathway Evidence Glyph Edge Colors

	Enzyme present. An enzyme for this reaction has been identified in this organism
	Enzyme absent. An enzyme for this reaction has not been identified in this organism
	Unique reaction. This reaction is unique to this pathway in the MetaCyc database
	Enzyme present by hole filler. An enzyme for this reaction has been identified in this organism by the Pathway Hole Filler
	Orphan reaction. No sequenced enzyme from any domain of life is known for this reaction
	Key reaction. The reaction has been designated a key reaction of this pathway
	Spontaneous/other. Used for spontaneous reactions, and for lines that do not denote reactions (e.g., denoting repetition in polymerization pathways)

Pathway Summary Statistics

Fraction of genes devoted to metabolism	1079 of 3744 (29%)
Base pathways	260
Total reactions in the base pathways	880
Base pathway reactions that are pathway holes	52 (6%)
Base pathway reactions that are not pathway holes	828 (94%)

Pathways Sorted by Pathway Score

Pathway score is a number between 0 and 1 inclusive that indicates the likelihood that a pathway is present; a higher number indiciates a higher likelihood. The pathway score is not a probability. Pathway scores are computed at pathway prediction time and are not updated later, such as due to editing of a pathway.

A pathway might have no pathway score if its presence was inferred by a curator, or if it is a super-pathway (super-pathways are not scored, and are not included in this page).

Pathways with a score less than the prediction threshold (default=0.15) are typically not predicted as present. An exception to this rule is a case where MetaCyc contains experimental evidence that the pathway exists in the exact organism for which pathway inference was performed, in which case the pathway will be imported from MetaCyc no matter its score.

Pathway	Pathway Glyph	Pathway Score	Total Rxns	Rxns Present in Vibrio cholerae O1 biovar El Tor str. N16961	Rxns Present in Other Pwys	Other Pwys	Key Rxns Present	In Taxonomic Range?	Links
cytochrome c biogenesis (system I type)		na	11	11	0	(none)	0 of 0	yes
norspermidine biosynthesis		na	6	6	0	(none)	4 of 4	yes
putrescine biosynthesis III		na	2	2	0	(none)	0 of 0	yes
spermidine biosynthesis II		na	4	4	0	(none)	2 of 2	yes
palmitate biosynthesis II (type II fatty acid synthase)		na	31	31	0	(none)	1 of 1	yes
GDP-2-N-[(2R)-2,4-dihydroxybutanoyl]-alpha-D-perosamine biosynthesis		na	5	4	0	(none)	0 of 0	yes
lipid A modification (glycine addition)		na	3	3	0	(none)	0 of 0	yes
L-glutamine biosynthesis I		na	1	1	0	(none)	0 of 0	yes
GDP-D-perosamine biosynthesis		na	2	2	0	(none)	1 of 1	yes
Kdo-lipid A biosynthesis (Vibrio cholerae serogroup O1 El Tor)		na	2	2	0	(none)	0 of 0	yes
guanosine nucleotides degradation III		0.151	4	2	0	(none)	0 of 0	yes
4-aminobutanoate degradation I		0.161	2	1	0	(none)	0 of 0	yes
reductive glycine pathway of autotrophic CO2 fixation		0.165	9	6	1	mixed acid fermentation pyruvate fermentation to acetate IV	0 of 0	yes
[2Fe-2S] iron-sulfur cluster biosynthesis		0.176	10	7	0	(none)	0 of 0	NO
thiosulfate oxidation III (multienzyme complex)		0.176	5	1	0	(none)	0 of 0	yes
L-threonine degradation I		0.176	6	4	0	(none)	0 of 0	yes
L-aspartate degradation II (aerobic)		0.195	3	2	0	(none)	0 of 0	yes
L-aspartate degradation III (anaerobic)		0.195	3	2	0	(none)	0 of 0	yes
guanine and guanosine salvage II		0.212	2	1	0	(none)	0 of 0	yes
4-aminobenzoate biosynthesis II		0.212	2	1	0	(none)	0 of 0	yes
6-hydroxymethyl-dihydropterin diphosphate biosynthesis I		0.213	5	3	0	(none)	1 of 1	yes
L-glutamine degradation I		0.225	1	1	0	(none)	0 of 0	yes
acetate and ATP formation from acetyl-CoA I		0.228	2	2	2	mixed acid fermentation pyruvate fermentation to acetate IV	0 of 0	yes
3-(4-hydroxyphenyl)pyruvate biosynthesis		0.231	1	1	0	(none)	0 of 0	yes
glycine biosynthesis I		0.231	1	1	0	(none)	0 of 0	yes
UTP and CTP dephosphorylation I		0.232	7	5	0	(none)	0 of 0	yes
geranyl diphosphate biosynthesis		0.233	1	1	0	(none)	0 of 0	yes
4-hydroxybenzoate biosynthesis II (bacteria)		0.239	1	1	0	(none)	0 of 0	yes
L-aspartate biosynthesis		0.239	1	1	0	(none)	0 of 0	yes
acetate conversion to acetyl-CoA		0.239	1	1	0	(none)	0 of 0	yes
cadaverine biosynthesis		0.239	1	1	0	(none)	0 of 0	yes
L-aspartate degradation I		0.239	1	1	0	(none)	0 of 0	yes
acetate and ATP formation from acetyl-CoA III		0.239	1	1	0	(none)	0 of 0	yes
UDP-alpha-D-glucose biosynthesis		0.244	2	2	0	(none)	0 of 0	yes
arginine dependent acid resistance		0.251	1	1	0	(none)	0 of 0	yes
NADP biosynthesis		0.251	1	1	0	(none)	0 of 0	yes
L-glutamate degradation I		0.251	1	1	0	(none)	0 of 0	yes
NADH to cytochrome bo oxidase electron transfer II		0.253	2	1	0	(none)	0 of 0	yes
L-glutamate biosynthesis I		0.254	2	2	0	(none)	0 of 0	yes
UDP-alpha-D-galactose biosynthesis		0.263	1	1	0	(none)	0 of 0	yes
L-serine degradation		0.263	3	1	0	(none)	0 of 0	yes
formate oxidation to CO2		0.263	na	na	0	(none)	0 of 0	yes
adenine and adenosine salvage I		0.263	2	2	0	(none)	0 of 0	yes
inosine 5'-phosphate degradation		0.267	4	3	0	(none)	0 of 0	yes
L-glutamate degradation II		0.281	2	2	0	(none)	0 of 0	yes
long-chain fatty acid activation		0.283	1	1	0	(none)	0 of 0	yes
hydroxymethylpyrimidine salvage		0.292	2	2	0	(none)	0 of 0	yes
5-oxo-L-proline metabolism		0.293	5	1	0	(none)	0 of 0	yes
peptidoglycan maturation		0.293	13	7	1	peptidoglycan biosynthesis	0 of 0	yes
bis(guanylyl molybdopterin) cofactor sulfurylation		0.293	3	1	0	(none)	0 of 0	yes
glutathione-peroxide redox reactions		0.293	3	1	0	(none)	0 of 0	yes
N-acetylglucosamine degradation I		0.302	2	2	0	(none)	0 of 0	yes
dipyrromethane cofactor biosynthesis		0.317	4	3	0	(none)	0 of 0	yes
tRNA-uridine 2-thiolation		0.32	8	8	0	(none)	0 of 0	yes
D-gluconate degradation		0.322	1	1	0	(none)	0 of 0	yes
alanine racemization		0.322	1	1	0	(none)	0 of 0	yes
L-threonine degradation IV		0.325	2	2	1	mixed acid fermentation	0 of 0	yes
tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate		0.328	2	2	0	(none)	0 of 0	yes
putrescine biosynthesis I		0.337	2	2	0	(none)	0 of 0	yes
sulfate activation for sulfonation		0.337	2	2	0	(none)	0 of 0	yes
L-arginine degradation III (arginine decarboxylase/agmatinase pathway)		0.337	2	2	0	(none)	0 of 0	yes
NAD phosphorylation and transhydrogenation		0.337	2	2	0	(none)	0 of 0	yes
adenosine nucleotides degradation II		0.352	5	3	0	(none)	1 of 1	yes
lipoate salvage I		0.353	2	2	0	(none)	0 of 0	yes
guanine and guanosine salvage I		0.353	2	2	0	(none)	0 of 0	yes
ethanol degradation I		0.368	2	2	2	mixed acid fermentation	1 of 1	yes
pyrimidine deoxyribonucleotides dephosphorylation		0.388	3	2	0	(none)	0 of 0	yes
trans, trans-farnesyl diphosphate biosynthesis		0.395	2	2	0	(none)	1 of 1	yes
glycerol degradation I		0.401	3	2	0	(none)	0 of 0	yes
L-citrulline degradation		0.401	3	2	1	L-arginine biosynthesis I (via L-ornithine)	1 of 1	yes
glycogen degradation II		0.401	6	5	0	(none)	0 of 0	yes
thiazole component of thiamine diphosphate biosynthesis I		0.408	6	5	0	(none)	0 of 0	yes
NAD salvage pathway III (to nicotinamide riboside)		0.419	3	2	0	(none)	2 of 2	yes
glutathione-glutaredoxin redox reactions		0.423	2	1	0	(none)	0 of 0	yes
L-asparagine degradation I		0.423	1	1	0	(none)	0 of 0	yes
glycine biosynthesis IV		0.423	1	1	0	(none)	0 of 0	yes
S-methyl-5'-thioadenosine degradation IV		0.423	1	1	0	(none)	0 of 0	yes
superoxide radicals degradation		0.423	2	2	2	reactive oxygen species degradation	0 of 0	yes
L-phenylalanine degradation I (aerobic)		0.423	1	1	0	(none)	0 of 0	yes
4-aminobenzoate biosynthesis I		0.423	2	2	0	(none)	0 of 0	yes
bis(guanylyl molybdenum cofactor) biosynthesis		0.423	2	2	0	(none)	0 of 0	yes
mannitol degradation I		0.423	2	2	0	(none)	0 of 0	yes
D-serine degradation		0.423	3	1	0	(none)	0 of 0	yes
acyl carrier protein activation		0.423	1	1	0	(none)	0 of 0	yes
citrate degradation		0.423	2	2	0	(none)	0 of 0	yes
autoinducer AI-2 biosynthesis II (Vibrio)		0.429	6	2	0	(none)	0 of 0	yes
gluconeogenesis I		0.431	13	13	5	mixed acid fermentation Entner-Doudoroff pathway	0 of 0	yes
N-acetylneuraminate and N-acetylmannosamine degradation I		0.432	4	4	0	(none)	0 of 0	yes
citrate lyase activation		0.437	5	3	0	(none)	0 of 0	yes
L-proline degradation I		0.44	3	2	0	(none)	1 of 1	yes
8-oxo-(d)GTP detoxification I		0.44	4	2	0	(none)	0 of 0	yes
Kdo transfer to lipid IVA (Vibrio cholerae serogroup O1 El Tor)		0.44	2	2	0	(none)	0 of 0	yes
L-cysteine degradation III		0.44	2	2	0	(none)	0 of 0	yes
thioredoxin pathway		0.44	2	1	0	(none)	0 of 0	yes
chitobiose degradation		0.44	2	2	0	(none)	0 of 0	yes
glycolysis		0.442	12	11	5	mixed acid fermentation Entner-Doudoroff pathway	0 of 0	yes
triacylglycerol degradation		0.477	3	1	0	(none)	1 of 1	yes
L-ornithine biosynthesis I		0.479	5	5	0	(none)	1 of 1	yes
TCA cycle		0.48	9	9	6	mixed acid fermentation	1 of 1	yes
pyrimidine deoxyribonucleosides salvage		0.484	5	4	0	(none)	0 of 0	yes
L-ascorbate degradation I (bacterial, anaerobic)		0.492	5	5	0	(none)	1 of 1	yes
ubiquinol-8 biosynthesis (early decarboxylation)		0.5	8	8	0	(none)	1 of 1	yes
folate transformations III		0.502	9	9	0	(none)	0 of 0	yes
pyrimidine ribonucleosides degradation		0.51	2	2	0	(none)	1 of 1	yes
adenosylcobalamin biosynthesis from adenosylcobinamide-GDP I		0.526	3	3	3	superpathway of adenosylcobalamin salvage from cobinamide I	1 of 1	yes
L-arginine degradation II (AST pathway)		0.528	5	4	0	(none)	0 of 0	yes
polyhydroxybutanoate biosynthesis		0.551	3	3	0	(none)	1 of 1	yes
UDP-N-acetyl-alpha-D-mannosaminouronate biosynthesis		0.56	2	2	0	(none)	0 of 0	yes
proline to cytochrome bo oxidase electron transfer		0.562	2	1	0	(none)	0 of 0	yes
Entner-Doudoroff shunt		0.562	2	2	0	(none)	0 of 0	yes
L-alanine biosynthesis I		0.566	2	2	0	(none)	0 of 0	yes
L-cysteine biosynthesis I		0.571	2	2	0	(none)	0 of 0	yes
4-amino-2-methyl-5-diphosphomethylpyrimidine biosynthesis I		0.571	2	2	0	(none)	0 of 0	yes
L-threonine degradation II		0.581	2	2	0	(none)	0 of 0	yes
5-(methoxycarbonylmethoxy)uridine biosynthesis		0.587	3	3	0	(none)	0 of 0	yes
benzoyl-CoA biosynthesis		0.587	3	3	0	(none)	0 of 0	yes
pyrimidine deoxyribonucleotides de novo biosynthesis I		0.598	9	9	0	(none)	1 of 1	yes
glycerophosphodiester degradation		0.601	2	2	0	(none)	0 of 0	yes
glutathione biosynthesis		0.601	2	2	0	(none)	0 of 0	yes
thiamine diphosphate biosynthesis		0.601	2	2	1	thiamine diphosphate salvage II	0 of 0	yes
xanthine and xanthosine salvage		0.601	2	2	0	(none)	0 of 0	yes
lipoate biosynthesis and incorporation I		0.601	2	2	0	(none)	0 of 0	yes
stearate biosynthesis II (bacteria and plants)		0.604	6	6	0	(none)	0 of 0	yes
lipoprotein posttranslational modification		0.629	7	6	0	(none)	2 of 2	yes
acyl carrier protein metabolism		0.652	2	2	0	(none)	0 of 0	yes
L-threonine biosynthesis		0.652	2	2	0	(none)	0 of 0	yes
gondoate biosynthesis (anaerobic)		0.66	4	3	0	(none)	1 of 1	yes
oleate biosynthesis IV (anaerobic)		0.687	14	14	0	(none)	1 of 1	yes
fatty acid beta-oxidation I (generic)		0.706	7	7	0	(none)	0 of 0	yes
myo-inositol biosynthesis		0.715	2	1	0	(none)	1 of 1	yes
trehalose degradation I (low osmolarity)		0.715	2	2	0	(none)	1 of 1	yes
palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)		0.756	9	9	0	(none)	3 of 3	yes
8-amino-7-oxononanoate biosynthesis I		0.769	11	11	0	(none)	2 of 2	yes
molybdenum cofactor biosynthesis		0.77	3	3	0	(none)	1 of 1	yes
(5Z)-dodecenoate biosynthesis I		0.835	6	6	0	(none)	2 of 2	yes
L-tryptophan degradation II (via pyruvate)		0.846	3	1	0	(none)	0 of 0	yes
pyruvate fermentation to (R)-acetoin II		0.856	2	2	0	(none)	1 of 1	yes
pyruvate fermentation to ethanol I		0.867	3	3	3	mixed acid fermentation pyruvate fermentation to acetate IV	0 of 0	yes
L-lysine biosynthesis I		0.87	9	9	0	(none)	1 of 1	yes
lipoate biosynthesis and incorporation II		0.876	2	2	0	(none)	1 of 1	yes
octaprenyl diphosphate biosynthesis		0.88	1	1	0	(none)	0 of 0	yes
phosphatidylserine and phosphatidylethanolamine biosynthesis I		0.88	2	2	0	(none)	0 of 0	yes
thiosulfate disproportionation IV (rhodanese)		0.88	1	1	0	(none)	0 of 0	yes
N6-L-threonylcarbamoyladenosine37-modified tRNA biosynthesis		0.88	2	2	0	(none)	0 of 0	yes
di-trans,poly-cis-undecaprenyl phosphate biosynthesis		0.88	2	2	0	(none)	0 of 0	yes
L-alanine degradation IV		0.88	1	1	0	(none)	0 of 0	yes
demethylmenaquinol-8 biosynthesis I		0.88	1	1	0	(none)	0 of 0	yes
L-glutamine degradation II		0.88	1	1	0	(none)	0 of 0	yes
L-alanine biosynthesis III		0.88	1	1	0	(none)	0 of 0	yes
melibiose degradation		0.88	1	1	0	(none)	0 of 0	yes
acyl-CoA hydrolysis		0.88	1	1	0	(none)	0 of 0	yes
CMP phosphorylation		0.88	2	2	0	(none)	0 of 0	yes
L-asparagine biosynthesis I		0.88	1	1	0	(none)	0 of 0	yes
guanylyl molybdenum cofactor biosynthesis		0.88	1	1	0	(none)	0 of 0	yes
fructose degradation		0.88	1	1	0	(none)	0 of 0	yes
adenosine nucleotides degradation III		0.88	1	1	0	(none)	0 of 0	yes
autoinducer CAI-1 biosynthesis		0.88	3	2	0	(none)	0 of 0	yes
acyl-[acyl-carrier protein] thioesterase pathway		0.88	1	1	0	(none)	0 of 0	yes
N-end rule pathway I (prokaryotic)		0.88	2	2	0	(none)	0 of 0	yes
bis(guanylyl tungstenpterin) cofactor biosynthesis		0.88	1	1	0	(none)	0 of 0	yes
3-dehydroquinate biosynthesis I		0.88	2	2	0	(none)	0 of 0	yes
menaquinol-8 biosynthesis		0.88	1	1	0	(none)	0 of 0	yes
PRPP biosynthesis		0.88	1	1	0	(none)	0 of 0	yes
polyphosphate metabolism		0.88	2	2	0	(none)	0 of 0	yes
guanine and guanosine salvage III		0.88	1	1	0	(none)	0 of 0	yes
ATP biosynthesis		0.88	1	1	0	(none)	0 of 0	yes
pyrimidine nucleobases salvage I		0.88	1	1	0	(none)	0 of 0	yes
ammonia assimilation cycle III		0.899	3	3	0	(none)	0 of 0	yes
L-tyrosine degradation I		0.925	5	4	0	(none)	0 of 0	yes
NADPH repair (prokaryotes)		0.927	4	2	0	(none)	1 of 1	yes
NADH repair (prokaryotes)		0.927	4	2	0	(none)	1 of 1	yes
formaldehyde oxidation VII (THF pathway)		0.932	4	3	0	(none)	0 of 0	yes
methylerythritol phosphate pathway I		0.94	9	8	0	(none)	1 of 1	yes
L-proline biosynthesis I (from L-glutamate)		0.989	4	3	0	(none)	0 of 0	yes
pyrimidine ribonucleosides salvage I		1.0	3	3	0	(none)	1 of 1	yes
S-adenosyl-L-methionine salvage I		1.0	4	4	0	(none)	2 of 2	yes
folate polyglutamylation		1.0	5	5	0	(none)	0 of 0	yes
ribose phosphorylation		1.0	2	2	0	(none)	1 of 1	yes
tRNA charging		1.0	21	21	0	(none)	0 of 0	yes
2-deoxy-alpha-D-ribose 1-phosphate degradation		1.0	3	3	1	mixed acid fermentation	0 of 0	yes
CDP-diacylglycerol biosynthesis II		1.0	4	4	0	(none)	0 of 0	yes
L-serine biosynthesis I		1.0	3	3	0	(none)	0 of 0	yes
heme b biosynthesis II (oxygen-independent)		1.0	4	4	0	(none)	1 of 1	yes
2,3-dihydroxybenzoate biosynthesis		1.0	3	3	0	(none)	0 of 0	yes
L-isoleucine biosynthesis I (from threonine)		1.0	7	5	0	(none)	1 of 1	yes
inosine-5'-phosphate biosynthesis I		1.0	6	6	0	(none)	3 of 3	yes
2-carboxy-1,4-naphthoquinol biosynthesis		1.0	7	6	0	(none)	1 of 1	yes
ectoine biosynthesis		1.0	5	5	0	(none)	1 of 1	yes
guanosine deoxyribonucleotides de novo biosynthesis II		1.0	4	4	0	(none)	2 of 2	yes
NAD de novo biosynthesis I (from aspartate)		1.0	5	5	0	(none)	0 of 0	yes
adenosylcobinamide-GDP salvage from cobinamide I		1.0	5	4	2	superpathway of adenosylcobalamin salvage from cobinamide I	0 of 0	yes
NAD salvage pathway II (PNC IV cycle)		1.0	5	5	0	(none)	0 of 0	yes
5-aminoimidazole ribonucleotide biosynthesis II		1.0	5	5	5	superpathway of 5-aminoimidazole ribonucleotide biosynthesis	0 of 0	yes
guanosine ribonucleotides de novo biosynthesis		1.0	4	4	0	(none)	0 of 0	yes
oleate beta-oxidation		1.0	35	35	0	(none)	0 of 0	yes
cardiolipin biosynthesis III		1.0	3	3	2	phosphatidylglycerol biosynthesis II (non-plastidic) phosphatidylglycerol biosynthesis I (plastidic)	1 of 1	yes
L-leucine biosynthesis		1.0	6	5	0	(none)	0 of 0	yes
purine deoxyribonucleosides degradation I		1.0	4	4	0	(none)	0 of 0	yes
L-methionine biosynthesis II		1.0	6	4	0	(none)	2 of 2	NO
UDP-N-acetyl-D-glucosamine biosynthesis I		1.0	5	5	0	(none)	0 of 0	yes
pyruvate fermentation to acetate II		1.0	3	3	3	mixed acid fermentation pyruvate fermentation to acetate IV superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass	1 of 1	yes
2-methylcitrate cycle II		1.0	6	6	0	(none)	1 of 1	yes
5-aminoimidazole ribonucleotide biosynthesis I		1.0	5	5	4	superpathway of 5-aminoimidazole ribonucleotide biosynthesis	0 of 0	yes
lipid IVA biosynthesis (Vibrio cholerae serogroup O1 El Tor)		1.0	6	6	0	(none)	0 of 0	yes
pyrimidine deoxyribonucleosides degradation		1.0	3	3	0	(none)	0 of 0	yes
cardiolipin biosynthesis I		1.0	3	3	2	phosphatidylglycerol biosynthesis I (plastidic) phosphatidylglycerol biosynthesis II (non-plastidic)	1 of 1	yes
purine ribonucleosides degradation		1.0	6	6	0	(none)	0 of 0	yes
UTP and CTP de novo biosynthesis		1.0	3	3	0	(none)	0 of 0	yes
glycogen biosynthesis I (from ADP-D-Glucose)		1.0	4	4	0	(none)	1 of 1	yes
adenine and adenosine salvage III		1.0	4	4	0	(none)	2 of 2	yes
tetrapyrrole biosynthesis I (from glutamate)		1.0	6	6	0	(none)	0 of 0	yes
aerobic respiration I (cytochrome c)		1.0	3	3	0	(none)	0 of 0	yes
L-methionine biosynthesis I		1.0	5	5	0	(none)	2 of 2	yes
heme b biosynthesis V (aerobic)		1.0	4	4	0	(none)	1 of 1	yes
pyruvate decarboxylation to acetyl CoA I		1.0	3	3	0	(none)	1 of 1	yes
L-tyrosine biosynthesis I		1.0	3	3	0	(none)	1 of 1	yes
adenosine deoxyribonucleotides de novo biosynthesis II		1.0	4	4	0	(none)	2 of 2	yes
glycine cleavage		1.0	3	3	0	(none)	1 of 1	yes
flavin biosynthesis I (bacteria and plants)		1.0	9	9	0	(none)	1 of 1	yes
CMP-3-deoxy-D-manno-octulosonate biosynthesis		1.0	5	4	0	(none)	1 of 1	yes
UDP-N-acetylmuramoyl-pentapeptide biosynthesis (Vibrio cholerae)		1.0	11	11	0	(none)	0 of 0	yes
chitin derivatives degradation		1.0	9	7	0	(none)	0 of 0	yes
chorismate biosynthesis from 3-dehydroquinate		1.0	5	5	0	(none)	0 of 0	yes
ppGpp metabolism		1.0	6	6	0	(none)	0 of 0	yes
tRNA processing		1.0	10	10	0	(none)	0 of 0	yes
GDP-mannose biosynthesis		1.0	4	4	0	(none)	0 of 0	yes
biotin-carboxyl carrier protein assembly		1.0	4	3	0	(none)	0 of 0	yes
phosphopantothenate biosynthesis I		1.0	4	4	0	(none)	0 of 0	yes
UMP biosynthesis I		1.0	6	6	1	L-arginine biosynthesis I (via L-ornithine)	1 of 1	yes
fatty acid elongation -- saturated		1.0	4	4	0	(none)	0 of 0	yes
L-tryptophan biosynthesis		1.0	6	6	0	(none)	0 of 0	yes
2-oxoglutarate decarboxylation to succinyl-CoA		1.0	3	3	0	(none)	1 of 1	yes
peptidoglycan recycling I		1.0	14	14	0	(none)	1 of 1	yes
CDP-diacylglycerol biosynthesis I		1.0	4	4	0	(none)	0 of 0	yes
fatty acid biosynthesis initiation (type II)		1.0	3	3	0	(none)	1 of 1	yes
pyridoxal 5'-phosphate biosynthesis I		1.0	7	7	0	(none)	0 of 0	yes
L-valine biosynthesis		1.0	4	4	0	(none)	0 of 0	yes
pentose phosphate pathway (non-oxidative branch) I		1.0	5	5	0	(none)	1 of 1	yes
adenosine ribonucleotides de novo biosynthesis		1.0	3	3	0	(none)	0 of 0	yes
D-galactose degradation I (Leloir pathway)		1.0	5	5	0	(none)	0 of 0	yes
adenine and adenosine salvage V		1.0	3	3	0	(none)	2 of 2	yes
ADP-L-glycero-beta-D-manno-heptose biosynthesis		1.0	5	5	0	(none)	1 of 1	yes
queuosine biosynthesis I (de novo)		1.0	4	4	0	(none)	0 of 0	yes
preQ0 biosynthesis		1.0	4	4	0	(none)	0 of 0	yes
siroheme biosynthesis		1.0	4	4	0	(none)	0 of 0	yes
2-aminoethylphosphonate degradation I		1.0	3	3	1	mixed acid fermentation	1 of 1	yes
molybdopterin biosynthesis		1.0	6	5	0	(none)	0 of 0	yes
adenosylcobalamin salvage from cobalamin		1.0	5	3	0	(none)	0 of 0	yes
L-histidine biosynthesis		1.0	10	10	0	(none)	0 of 0	yes
biotin biosynthesis from 8-amino-7-oxononanoate I		1.0	4	4	0	(none)	1 of 1	yes
pyrimidine deoxyribonucleotide phosphorylation		1.0	4	4	0	(none)	0 of 0	yes
L-homoserine biosynthesis		1.0	3	3	0	(none)	0 of 0	yes
chitin degradation II (Vibrio)		1.0	6	6	0	(none)	1 of 1	yes
coenzyme A biosynthesis I (prokaryotic)		1.0	4	4	0	(none)	1 of 1	yes
L-phenylalanine biosynthesis I		1.0	3	3	0	(none)	1 of 1	yes
formate assimilation into 5,10-methylenetetrahydrofolate		1.0	3	3	0	(none)	1 of 1	yes
pentose phosphate pathway (oxidative branch) I		1.0	3	3	2	superpathway of glycolysis and the Entner-Doudoroff pathway Entner-Doudoroff pathway	0 of 0	yes
L-histidine degradation I		1.0	4	4	0	(none)	0 of 0	yes
NAD de novo biosynthesis IV (anaerobic)		1.0	6	6	0	(none)	0 of 0	yes
glyoxylate cycle		1.0	6	6	4	mixed acid fermentation	2 of 2	yes

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